Infantile hemangiomas are arrested in an early developmental vascular differentiation state
نویسندگان
چکیده
منابع مشابه
Infantile Hemangiomas: An Update on Pathogenesis
Infantile hemangiomas (IHs) are the most common vascular tumors of childhood, affecting ∼5% of all infants. Although most lesions proliferate and then involute with minimal consequence, a significant minority can be disfiguring, functionally significant, or, rarely, lifethreatening. Recent discoveries concerning hemangioma pathogenesis provide both an improved understanding and more optimal app...
متن کاملPropranolol for infantile hemangiomas: early experience at a tertiary vascular anomalies center.
OBJECTIVES/HYPOTHESIS Propranolol has recently been introduced as a novel pharmacologic treatment for infantile hemangiomas. Systematic examination of this treatment in a tertiary care setting has not been described. This study explores the impact of propranolol on both proliferative and involuting hemangiomas at a tertiary vascular anomalies center. STUDY DESIGN Retrospective single institut...
متن کاملInfantile Hemangiomas: An Update on Pathogenesis
Infantile hemangiomas (IHs) are the most common vascular tumors of childhood, affecting ∼5% of all infants. Although most lesions proliferate and then involute with minimal consequence, a significant minority can be disfiguring, functionally significant, or, rarely, lifethreatening. Recent discoveries concerning hemangioma pathogenesis provide both an improved understanding and more optimal app...
متن کاملInfantile Hemangiomas: An Update on Pathogenesis
Infantile hemangiomas (IHs) are the most common vascular tumors of childhood, affecting ∼5% of all infants. Although most lesions proliferate and then involute with minimal consequence, a significant minority can be disfiguring, functionally significant, or, rarely, lifethreatening. Recent discoveries concerning hemangioma pathogenesis provide both an improved understanding and more optimal app...
متن کاملPropranolol for Infantile Hemangiomas
Hemangiomas are common vascular birthmarks that usually present a predictable pattern of proliferation and ultimate involution. Most do not require any treatment. When intervention is clinically indicated, medical and surgical options exist. Historically, corticosteroids have been used and have been shown to slow or stop the growth of a majority of hemangiomas; however, growth concerns and infe...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2004
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.3800153